Author’s response to reviews Title: Antitumor effects of Quercetin on Y79 retinoblastoma cells via JNK and p38 MAPK pathways Authors:
نویسندگان
چکیده
Nitin Telang, Ph.D (Reviewer 1): Overall, the manuscript is reasonably well written and contains good data on anti-proliferative and pro-apoptotic effects of Quercetin on Y79 retinoblastoma cell line. The study outcome provides convincing evidence for the involvement of the JNK and p38MAPK pathways in growth inhibitory efficacy. However, the following points need to be considered and appropriately addressed.
منابع مشابه
Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways
BACKGROUND Quercetin (QCT) is a flavonol present in many vegetables, it is proved to show chemo preventive effect against lung, cervical, prostate, breast and colon cancer due to its anti-inflammatory, anti-tumor and anti-oxidant property. Looking into the reported chemo-preventive effect we speculated antitumor activity in retinoblastoma (RB) Y79 cells, we also studied the molecular mechanism ...
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